This study investigated the anti-insulin resistant activity of red pitaya (Hylocereus polyrhizus) fruit. Fresh pitaya along with two heat-processed pitaya samples with different proportions of phenolic contents, scavenging activities, and soluble dietary fibers were tested in insulin resistant rats over 6 weeks of treatment in a cause-effect study to investigate the anti-insulin resistant components of red pitaya. The results showed that fresh pitaya significantly (p < 0.05) attenuated the insulin resistance, hypertriglyceridemia and atherosclerotic changes induced by fructose supplement in rats. Thermallytreated pitaya at 95 C for 30 min (containing a low antioxidant content) significantly (p < 0.05) improved hyperinsulinemia. Thermally-treated pitaya at 105 C for 60 min (containing a low antioxidant and soluble dietary fiber content) fed to rats had no significant effect on insulin resistance, dyslipidemia and atherogenesis. Based on this study, the anti-insulin resistant effect of red pitaya can be attributed to its antioxidant and soluble dietary fiber contents.
کلید واژگان :Anti-diabetic activity, red pitaya (Hylocereus polyrhizus) fruit
ارزش ریالی : 600000 ریال
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