This study was designed to evaluate the effects of oral administration of Echinacea hydroethanolic extract on the dog’s immune system. The study was performed on 14 dogs that were referred to the veterinary clinic. These dogs were randomly allocated to 2 equal treatment groups. The first group received 1 mL of 5 % Echinacea hydroethanolic extract two times a day for two months and the second group received a placebo (water). In order to do hematology and immunology tests, the dogs were bled on days 0, 30 and 60. Blood tests, including packed cell volume (PCV), haemoglobin (Hb), red blood cell count (RBC), white blood cell count (WBC), counting neutrophils (Nut), lymphocytes (Lym), monocytes (Mon), eosinophils (Eos), basophils (Baso), and B Cell, were performed. Furthermore, safety factor IgM and percent of phagocytosis and phagocyte were measured on the blood sample. The results showed that in the group which received Echinacea PCV, Hb, RBC count, WBC count, Lym, Nut, the percent of phagocytosis and IgM significantly increased (P <0.05). Moreover, positive effects of Echinacea plant on the immune system were observed. There was a significant change in HTC, RBC, HB over time in the group that received Echinacea and the percent of phagocytosis and IgM (P <0.05). The study establishes that these extracts might have appreciable immunostimulatory activity. However, further studies are required to confirm these findings.
کلید واژگان :Echinacea, oral administration, dog, immune system
ارزش ریالی : 600000 ریال
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