Abstract: Introduction: Tea tree oil (TTO), or melaleuca oil, is an essential oil with a fresh camphoraceous odor and a color that ranges from pale yellow to clear. It has shown promise as an antimicrobial agent. It is said that it can be effective in a variety of dermatologic conditions, including dandruff, acne, lice, herpes, and other skin infections. Objective: The major goal of this study was to investigate antimicrobial and wound healing effects of tea tree oil in rabbits. Material and methods: A total number of twenty white New Zealand rabbits were divided into two groups in which number of males and females was equal. In the first group a sterile wound was created by burning the skin. In the second group wounds were infected by Staphylococcus aureus(MRSA) using McFarland tubes. For each wound one drop of Staphylococcus aureus was spilled. In each group two subjects were claimed as control. Then sampling was done on seventh, fifteenth and twenty first days. Samples were both pathologically and morphologically studied. Statistical analysis was performed using the χ2 test and Fisher's exact test. Conclusion: Infected subjects were all healed. Although amongst the first group, in which a sterile burn wound was created, females showed better results.
کلید واژگان :Wound healing, Tea tree oil, burn wound, infected wound, Methicillin Resistant Staphylococcus aureus
ارزش ریالی : 300000 ریال
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