Background. – Allergic rhinitis is one of the most prevalent diseases worldwide and several studies have been done to investigate its risk factors.Some studies have shown that there is an association between severity of allergic rhinitis and serum level of 25 OH vitamin D, but no consensushas been yet achieved.Objective. – Given the high prevalence of allergic rhinitis and the high prevalence of vitamin D deficiency in Iranian population, this study aimedto determine the mean serum level of vitamin D in patients with allergic rhinitis and the control group.Materials and methods. – This is a case-control study conducted in Imam Ali Clinic in Shahrekord (Iran) during 2014–2015. Fifty-four patientswith allergic rhinitis and 54 healthy person were randomly selected and their serum levels of 25 OH vitamin D were measured. Also, demographicdata and the data on severity of allergic rhinitis were collected by a questionnaire and analyzed by SPSS.Results. – The mean serum level of 25 OH vitamin D in the case and the control groups were 29.62 ± 18.44 nmoL (11.8 ± 7.4 ng/mL) and62.18 ± 18.53 nmoL (24.9 ± 7.4 ng/mL), respectively, with a statistically difference between the two groups (P = 0.001). Also, 4 (7.4%) patientsin case group were vitamin D deficient but no one in the control group was vitamin D deficient, with a statistically difference between the twogroups according to the Fisher’s exact test (P = 0.003).Conclusion. – According to the results of this study, there is a relationship between serum level of vitamin D and suffering from allergic rhinitis.Special attention should be paid to the geographic characteristics of Chaharmahal and Bakhtiari province. Certain health programs should beimplemented to cure and prevent vitamin D deficiency in allergic rhinitis patients.
کلید واژگان :Allergic rhinitis; Allergy; Vitamin D; 25-hydroxy-vitamin D; Allergen
ارزش ریالی : 600000 ریال
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