Fe3O4@SiO2-imid-PMAn efficiently catalyzes
the condensation reaction of isatoic anhydride, aldehydes,
and primary amines or ammonium salts to afford the corresponding
2,3-dihydroquinazolin-4(1H)-one derivatives
under ultrasonic irradiation or reflux conditions. This
method gives notable advantages such as operational simplicity,
excellent yields, short reaction times, and absence
of any tedious workup or purification. In addition, the
excellent catalytic performance and the easy preparation,
thermal stability, and separation of the catalyst make it a
good heterogeneous system and a useful alternative to
other heterogeneous catalysts. Also, the aforementioned
nanocatalyst can be easily recovered by a magnetic field
and reused for subsequent reactions for at least six times
without noticeable deterioration in catalytic activity and
reaction yield.
کلید واژگان :
2,3-dihydroquinazolin-4(1H)-ones ● Magnetic nanocatalyst ● one-pot synthesis ● Green synthesis ● Ultrasonic irradiation
