Background: Blood concentrations and oxygen saturation levels are important biomarkers for breast cancer diagnosis. Objectives: In this study, the absorption coefficient of hemoglobin (Hb) was used to distinguish between normal and abnormal breast tissue. Materials and Methods: A near-infrared source (637 nm) was transmitted from major and minor vessels of a breast phantom containing 2, 4 concentrations of oxy- and deoxy-Hb. The absorption coefficients were determined from spectrometer (SM) and powermeter (PM) data. Results: The absorption coefficients were 0.075 0.026 cm-1 for oxygenated Hb (normal) in major vessels and 0.141 0.023 cm-1 at 4 concentration (abnormal) with SM, whereas the breast absorption coefficients were 0.099 0.017 cm-1 for oxygenated Hb (normal) in minor vessels and 0.1710.005 cm-1 at 4concentrations with SM. A comparison of the data obtained using a SM and a PM was not significant statistically. Conclusion: The study of the absorption coefficient data of different concentrations of Hb in normal and abnormal breasts via the diffusion of near-infrared light is a valuable method and has the potential to aid in early detection of breast abnormalities with SM and PM in major and minor vessels.
کلید واژگان :Hemoglobin, Optical Properties, Near Infrared Spectroscopy, Absorption Coefficient
ارزش ریالی : 1200000 ریال
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